Insights from cardiovascular magnetic resonance imaging supporting the selfish brain hypothesis of arterial hypertension

نویسندگان

  • Jonathan C Rodrigues
  • Emma C Hart
  • Neelam Hassan
  • Mandy Williams
  • Amy E Burchell
  • Laura E Ratcliffe
  • Angus K Nightingale
  • Julian F Paton
  • Nathan E Manghat
چکیده

Background Brainstem hypoperfusion may evoke systemic hypertension as a mechanism to boost cerebral blood flow: the selfish brain hypothesis. This notion is supported by evidence of vertebral artery hypoplasia (VAH) in hypertensive rat models. We determined the prevalence of anatomical variations of posterior cerebral circulation which could predispose to brainstem hypoperfusion in a hypertensive human cohort.

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عنوان ژورنال:

دوره 17  شماره 

صفحات  -

تاریخ انتشار 2015